James, 41, launched his quest for a fifth NBA championship with 14 points and seven assists in a 106-100 defeat of the reigning NBA champions at Madison Square Garden.
But despite an encouraging first win in a Philadelphia uniform, James was keeping his feet firmly on the ground.
"It's going to take some time," James said of the Sixers new-look line-up. "It's just one game, but obviously we can learn from the good things that we did."
James though was happy that the Sixers showed signs of development during Tuesday's opener.
"We're still new to each other," he said. "We will have some bumps in the road at times. But I mean, I think tonight when we had those bumps in the roads we were able able to use what happened previously and then make the adjustment."
James was the highest-profile addition to the Sixers roster in the offseason, and joins a Philadelphia team also bolstered by the arrival of Jaylen Brown from Boston.
James said Brown, the NBA Finals Most Valuable Player in 2024 during the Celtics' championship season, would help foster a winning culture in Philly.
"He's just another guy that can hold guys accountable because they understand, they see a guy that has gotten to the finish line," James said of Brown.
"It's definitely very helpful. These guys that's been here are trying to be able to get to that point, obviously this is a marathon, and we're not going to do it in day one.
"But the experience that we have, the experience that we bring to this ball club, hopefully we can translate it to to wins and more."
James intends to lead by example in the Sixers locker room.
"I'm there before everybody gets to the gym, and I'm one of the last ones to leave," James said. "I don't just be like telling guys to do it.
"I hold myself accountable, and if I'm not doing something, I want the guys to hold me accountable. So I think that that goes a long way."
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