St Kilda v Western Bulldogs (Thursday, 7:30pm AEST)
St Kilda: Jack Macrae and Liam Stocker are in for Mattaes Phillipou and Hugh Boxshall. Jack Sinclair plays his 200th game.
FB: Isaac Keeler, Callum Wilkie, Jimmy Webster
HB: Marcus Windhager, Nasiah Wanganeen-Milera, Ryan Byrnes
C: Mason Wood, Jack Sinclair, Tobie Travaglia
HF: Jack Higgins, Zak Jones, Bradley Hill
FF: Cooper Sharman, Anthony Caminiti, Mitch Owens
R: Rowan Marshall, Hunter Clark, Jack Steele
(Bench: Jack Macrae, Liam Stocker, Dan Butler, Jack Carroll, Max Hall)
Western Bulldogs: Sam Darcy and Cooper Hynes are in for Ryan Gardner and James Harmes.
FB: Luke Cleary, James O'Donnell, Bailey Williams
HB: Lachie Bramble, Rory Lobb, Bailey Dale
C: Sam Davidson, Ed Richards, Joel Freijah
HF: Ryley Sanders, Aaron Naughton, Matthew Kennedy
FF: Laitham Vandermeer, Sam Darcy, Rhylee West
R: Tim English, Marcus Bontempelli, Tom Liberatore
(Bench: Josh Dolan, Cooper Hynes, Buku Khamis, Lachlan McNeil, Adam Treloar)
Hawthorn v Adelaide (Friday, 7:40pm AEST)
Hawthorn: Henry Hustwaite and Nick Watson are in for James Worpel and Finn Maginness.
FB: Josh Battle, Tom Barrass, Karl Amon
HB: Jarman Impey, Josh Weddle, Massimo D'Ambrosio
C: Connor MacDonald, Henry Hustwaite, Harry Morrison
HF: Blake Hardwick, Sam Butler, Dylan Moore
FF: Max Ramsden, Mabior Chol, Jack Ginnivan
R: Lloyd Meek, Jai Newcombe, Josh Ward
(Bench: Seamus Mitchell, Conor Nash, Jack Gunston, Nick Watson, Changkuoth Jiath)
Adelaide: Lachlan Murphy is in for James Peatling. Ben Keays plays his 150th game.
FB: Josh Worrell, Jordon Butts, Wayne Milera
HB: Max Michalanney, Mark Keane, Rory Laird
C: Isaac Cumming, Jordan Dawson, Dan Curtin
HF: Ben Keays, Riley Thilthorpe, Lachlan Murphy
FF: Darcy Fogarty, Taylor Walker, Alex Neal-Bullen
R: Reilly O'Brien, Izak Rankine, Sam Berry
(Bench: Josh Rachele, Brodie Smith, Mitchell Hinge, Luke Pedlar, Jake Soligo)
Brisbane v GWS Giants (Saturday, 1:20pm AEST)
Brisbane: Brandon Starcevich and Sam Day are in for Deven Robertson and Ty Gallop.
FB: Dayne Zorko, Jack Payne, Ryan Lester
HB: Noah Answerth, Harris Andrews, Brandon Starcevich
C: Jaspa Fletcher, Hugh McCluggage, Jarrod Berry
HF: Charlie Cameron, Eric Hipwood, Will Ashcroft
FF: Cam Rayner, Logan Morris, Callum Ah Chee
R: Darcy Fort, Josh Dunkley, Lachie Neale
(Bench: Kai Lohmann, Levi Ashcroft, Sam Day, Zac Bailey, Darcy Wilmot)
GWS Giants: Finn Callaghan and Harry Rowston are in for Jacob Wehr and Toby McMullin.
FB: Connor Idun, Sam Taylor, Leek Aleer
HB: Lachie Whitfield, Jack Buckley, Lachie Ash
C: Xavier O'Halloran, Toby Bedford, Josh Kelly
HF: Brent Daniels, Aaron Cadman, Darcy Jones
FF: Callum Brown, Jesse Hogan, Toby Greene
R: Nicholas Madden, Finn Callaghan, Tom Green
(Bench: Harvey Thomas, Harry Himmelberg, Harry Rowston, Jake Riccardi, Joe Fonti)
Essendon v Geelong (Saturday, 4:15pm AEST)
Essendon: Debutants Archer May and Lachlan Blakiston are in for Ben Hobbs and Sam Durham.
FB: Andrew McGrath, Jayden Laverde, Archie Roberts
HB: Zak Johnson, Jaxon Prior, Angus Clarke
C: Xavier Duursma, Zach Merrett, Luamon Lual
HF: Archie Perkins, Nate Caddy, Nic Martin
FF: Archer May, Peter Wright, Isaac Kako
R: Todd Goldstein, Jye Caldwell, Darcy Parish
(Bench: Jade Gresham, Will Setterfield, Matt Guelfi, Archer Day-Wicks, Lachlan Blakiston)
Geelong: Bailey Smith is in for Ted Clohesy.
FB: Jack Henry, Sam De Koning, Connor O'Sullivan
HB: Lawson Humphries, Tom Stewart, Zach Guthrie
C: Mark Blicavs, Max Holmes, Oliver Dempsey
HF: Gryan Miers, Shaun Mannagh, Brad Close
FF: Tyson Stengle, Jeremy Cameron, Patrick Dangerfield
R: Rhys Stanley, Bailey Smith, Tom Atkins
(Bench: Mitch Duncan, Oisin Mullin, Shannon Neale, Mark O'Connor, Jack Martin)
North Melbourne v Fremantle (Saturday, 7:35pm AEST)
North Melbourne: Kallan Dawson is in for Charlie Comben.
FB: Kallan Dawson, Toby Pink, Griffin Logue
HB: Riley Hardeman, Caleb Daniel, Luke McDonald
C: Dylan Stephens, Luke Davies-Uniacke, Jy Simpkin
HF: Tom Powell, Nick Larkey, Colby McKercher
FF: Paul Curtis, Jack Darling, Cameron Zurhaar
R: Tristan Xerri, George Wardlaw, Harry Sheezel
(IC: Finn O'Sullivan, Zac Fisher, Luke Parker, Jacob Konstanty, Robert Hansen Jr)
Fremantle are unchanged. Corey Wagner and Matthew Johnson play their 50th games.
FB: Luke Ryan, Josh Draper, Brennan Cox
HB: Heath Chapman, Corey Wagner, Jordan Clark
C: Jeremy Sharp, Shai Bolton, Matthew Johnson
HF: Michael Frederick, Sam Switkowski, Murphy Reid
FF: Patrick Voss, Josh Treacy, Jye Amiss
R: Luke Jackson, Caleb Serong, Andrew Brayshaw
(Bench: Bailey Banfield, Neil Erasmus, Nat Fyfe, Sean Darcy, Karl Worner)
Port Adelaide v Melbourne (Sunday, 3:20pm AEST)
Port Adelaide: Jason Horne-Francis is in for Jeremy Finlayson. Jordon Sweet, Logan Evans and Mani Liddy join the extended bench.
FB: Brandon Zerk-Thatcher, Esava Ratugolea, Miles Bergman
HB: Kane Farrell, Aliir Aliir, Ryan Burton
C: Jase Burgoyne, Jason Horne-Francis, Willem Drew
HF: Darcy Byrne-Jones, Sam Powell-Pepper, Ollie Wines
FF: Willie Rioli, Mitch Georgiades, Joe Richards
R: Dante Visentini, Connor Rozee, Zak Butters
(Bench: Jordon Sweet, Hugh Jackson, Christian Moraes, Logan Evans, Travis Boak, Jackson Mead, Josh Sinn, Mani Liddy)
Melbourne: Jack Viney is back in the starting 18. Tom McDonald and Harry Sharp join the extended bench.
FB: Jake Bowey, Steven May, Christian Salen
HB: Judd McVee, Jake Lever, Daniel Turner
C: Kade Chandler, Christian Petracca, Xavier Lindsay
HF: Harvey Langford, Bayley Fritsch, Tom Sparrow
FF: Jake Melksham, Harrison Petty, Kysaiah Pickett
R: Max Gawn, Clayton Oliver, Jack Viney
(Bench: Jacob van Rooyen, Caleb Windsor, Koltyn Tholstrup, Ed Langdon, Blake Howes, Trent Rivers, Tom McDonald, Harry Sharp)
West Coast v Carlton (Sunday, 6:10pm AEST)
West Coast: Noah Long, Clay Hall, Bailey J. Williams and the debuting Tom McCarthy join the extended bench. Tom Cole is out.
FB: Reuben Ginbey, Harry Edwards, Ryan Maric
HB: Liam Duggan, Sandy Brock, Liam Baker
C: Tyrell Dewar, Brady Hough, Jayden Hunt
HF: Jack Graham, Jack Williams, Liam Ryan
FF: Jamie Cripps, Oscar Allen, Elijah Hewett
R: Matt Flynn, Tim Kelly, Harley Reid
(Bench: Tyler Brockman, Noah Long, Archer Reid, Bo Allan, Clay Hall, Bailey J. Williams, Jack Hutchinson, Tom McCarthy)
Carlton: Corey Durdin, Lewis Young and Jordan Boyd join the extended bench.
FB: Mitch McGovern, Jacob Weitering, Adam Saad
HB: Oliver Hollands, Jack Silvagni, Sam Docherty
C: Nick Haynes, Patrick Cripps, Sam Walsh
HF: Alex Cincotta, Hudson O'Keeffe, Lochie Fogarty
FF: Jesse Motlop, Charlie Curnow, Zac Williams
R: Tom De Koning, Adam Cerra, George Hewett
(Bench: Matt Carroll, Cooper Lord, Orazio Fantasia, Blake Acres, Corey Durdin, Will White, Lewis Young, Jordan Boyd)