The Springboks take on Japan at Wembley Stadium in London on November 1 before travelling to Paris to meet France a week later in a repeat of their 2023 Rugby World Cup quarter-final.
They tackle Italy in Turin on November 15 before the latest instalment of their burgeoning grudge match with Ireland in Dublin on November 22.
They finish the tour against Wales in Cardiff a week later.
Erasmus selected his squad earlier on Monday and made several left-field picks, providing opportunities to players who have either not yet been in the mix this season or returned from long-term injury.
Here are five to watch, some who have played this year and others who will wear the green and gold for the first time.
The Stormers flanker, who can also play in the second row, is no youngster at the age of 27, but has been a consistent performer in the United Rugby Championship and has caught the eye of Erasmus. His mobility and work-rate are key assets, and he will hope to add to his five caps earned in 2024 somewhere along the line. He looked a little out of his depth at times in his debut season in international rugby, but clearly Erasmus feels there is a player there he can work with. His breakdown work and defence are other top attributes.
Hooker was a feature on the wing in the Rugby Championship in the absence of Kurt-Lee Arendse, who has since returned and is likely to win back his place for Paris and Dublin especially. But Hooker, whom many see as an outside centre in the long-term, has many fine attributes, and unlike Arendse is a big unit in the wide channels. He is a powerful runner, good under the high ball and certainly quick, and seems to have learned the Springbok defensive pattern well. How he is used on this tour will be fascinating.
A left-field pick of a prop who has barely played for the Stormers and would likely not have got his chance this season were it not for an injury crisis in the front row for the Cape Town side. But Porthen is obviously a player that has been watched for some time by Erasmus, who does not make decisions on a whim, and as a former Junior Springbok captain certainly has pedigree. The tighthead has impressed for the Stormers in the early part of this campaign and, with matches to come against, with the greatest respect, not the most powerful scrums in Japan, Italy and Wales, it is a good opportunity to see what he is all about firsthand. He is the only uncapped member of the squad.
Loosehead prop Steenekamp became a regular last year with the Springboks after making his debut in 2022 but has not featured in 2025 after being sidelined with a knee injury since March. He returned for the Bulls in recent weeks and, having proven his fitness, is straight back into the mix for Erasmus. Raised on the hard fields of Potchefstroom, he is also no youngster at 28 but is viewed as one of the best scrummagers in the country. Steenekamp will be back-up to Ox Nche on this tour but is a superbly able replacement.
The versatile back is cut in very much the same mould as Cheslin Kolbe and Kurt-Lee Arendse, though he is perhaps not quite at their level yet. They are similar players — smaller in stature, but fast and equally ferocious in the tackle. Van der Merwe has been a wing for most of his career but has popped up in the fullback position for the Sharks this season as well. With Damian Willemse the only specialist fullback in the squad (unless we are counting Sacha Feinberg-Mngomezulu too), Van der Merwe is one of several who can fill in at the back if needed.