Teams that start their respective series at home and go down 3-2 have only gone on to win it 22% of the time, leaving the odds in the Flyers' favor.
Crosby finished the game with two clutch assists, despite getting hurt in the second, and almost scored a goal after barely missing the empty net at the end of the game.
Pittsburgh now became the sixth team since 2016 to force a Game 6 after going down 3-0 in the series.
The series now heads to Philadelphia for Game 6 on April 29th.
Recap & Highlights
It didn't even take two minutes for things to get heated between the two rivals.
Pittsburgh's Evgeni Malkin flipped the puck into the Flyers' bench after a whistle before the two sides would get into it.
It only took one shot and almost three minutes for the Penguins to get on the board first.
Elmer Soderblom picked up his first career playoff goal, with assists by Anthony Mantha and Parker Wotherspoon, who both picked up their first, to make it a 1-0 game.
Almost 13 minutes after the goal, things got tense between Malkin and Garnet Hathaway, who received a two-minute penalty for tripping, then a two-minute minor for roughing after his scrum with Malkin.
Mantha and Travis Konecny also received penalties after the heated exchange.
Despite both teams putting up a combined 20 shots on goal and one power play each, the score remained at 1-0 heading into the second period, which also didn't waste any time getting to see numbers on the scoreboard.
Connor Dewar scored his second of the playoffs, with assists by Crosby (3) and Blake Lizotte (2), to make it a 2-0 game just three minutes into the period.
Philadelphia grew tired quickly of the Penguins fans' cheers and decided to cut the lead back to one.
Then, 12 seconds later, Alex Bump scored his first career playoff goal with assists by Rasmus Ristolainen (3) and Noah Cates (2) to make it 2-1.
That is now the second-fastest time scored between both teams in a 'Battle of Pennsylvania' playoff game since their 2012 Conference Quarterfinals Game 2 matchup, when they scored six seconds apart.
The Flyers' power play, which only got off one shot on goal in their first attempt, couldn't get anything done the second time around. Outside of going 2-for-3 on the power play in Game 3, the Flyers were 0-for-12 in all other chances during the series after another opportunity.
Crosby hobbled towards the bench and exited the game with under seven minutes to go in the second after taking a wrist shot from teammate Ryan Shea.
And, in the most typical Flyers-Penguins fashion, as soon as Crosby leaves the ice, the Flyers immediately tie things up and take advantage.
Travis Sanheim made it a 2-0 game with his second goal of the playoffs, with assists by Ristolainen (4), his second of the game, and Travis Konecny (3).
Sanheim became the fourth Flyers defenseman in the past 20 years to score more than one goal in a single playoff series, joining Ivan Provorov (2020), Andrew MacDonald (2018), and Chris Pronger (2010).
Then, two minutes later, Pittsburgh would score the most video-game-like goal humanly possibly after Crosby returned to the ice.
Kris Letang ripped one from the blue line that would bounce off the boards, hit Flyers goaltender Dan Vladar from behind, and bounce into the net behind him to make it 3-2.
Crosby recorded his second of the assist of the game, along with Rhea's first of the playoffs, who initially injured Crosby earlier.
It marked Letang's 92nd playoff point with one franchise, tying the legend Bobby Orr for the eighth-most in NHL history.
Nothing would be done in the third period as the Flyers held the Penguins to just four shots on goal, and the reverse to just six.
Pittsburgh outshot Philly 21-20, while the latter led in hits 42-37. Both teams finished 0-for-2 on their respective power plays.