The performance came just a month after Wilson's emotional exit from the UK Championship in York, where he was forced to use a replacement cue following damage to his own.
That campaign ended with a 6-4 first-round defeat by Elliot Slessor and a visibly upset Wilson admitting afterwards that he had been "close to a mental breakdown".
Now settled with a new cue that he has been using for around a month, the reigning world champion and 2025 Masters runner-up was comfortable throughout.
Wilson potted 10 reds and 10 blacks as he briefly threatened a maximum break before the run ended on 80.
Former World Championship semi-finalist Si fought back to 3-2 at one stage, but the balance of the match shifted decisively thereafter. Wilson raised his level, taking the next three frames in a row to pull clear.
Frame seven brought a break of 101 that marked the 545th century of his career, capped by a no-look shot on the black to reach three figures. He followed that with a further century, a smooth 105, to complete the victory.
"It has been a really tough time, so I thank you for all the love you have given me; it really lifted me," Wilson said afterwards.
"This venue can bring the best out of you. I still have a lot of time in this game, so hopefully I can conquer this venue for a long time."
"I felt I had let people down, and I felt a bit silly. Having a cue I'm happy with, I'm just so excited I can deliver - the cue is so important. I felt very similar to how I've been over the past 18 months, bar the last six months.
"When you go out there and can't trust what you're using, you have no chance. I think this cue is better because there's a bit more power, a bit more whip, and it's about learning how to control that - I've had a month to get used to it, I've had to modify my cue action."
The 6-2 result carried an odd statistical footnote, with all five matches played so far in this year's tournament ending in the same scoreline.
Wilson faces either Neil Robertson or Chris Wakelin in the next round.