The previous record was nine minutes, set by Andre Drummond in 2022.
Wemby, 22, finished the game with 41 points (17-27) with 16 rebounds, four assists, three blocks, and a steal as the Spurs went on to beat the Chicago Bulls 129-114, extending their now nine-game win streak.
It's just another milestone as the French superstar continues to make his case for MVP this season. He's averaging 24.2 points, 11.3 rebounds, and a league-leading 3.1 blocks per game - no other player averages more than 1.8.
San Antonio are on the path for the NBA Finals this year as they currently rank second in the Western Conference with a 57-18 record, sitting just two games behind the Oklahoma City Thunder, a team the Spurs are 4-1 against this season.
Since February 1st, the Spurs are a jaw-dropping 25-2.
"The most fun part is that we've got a healthy locker room and we're just happy as a whole because we get on together well on and off the court," said Wembanyama after the game. "We're just loving the experience."